herbicide metazachlor CAS No.:67129-08-2 98%TC 50%SC 10%EC CAS NO.67129-08-2

 Common name :metazachlor (BSI, E-ISO); métazachlore ((m) F-ISO)

 IUPAC name 2-chloro-N-(pyrazol-1-ylmethyl)acet-2',6'-xylidide 

 Chemical Abstracts name 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide 
CAS RN [67129-08-2] 

EEC no. 266-583-0 

Development codes BAS 479 00 H (BASF)

 PHYSICAL CHEMISTRY

Composition Tech. is ≥94% pure. 

Mol. wt. 277.8  M.f. C14H16ClN3O 

Form Yellowish crystals; (tech., beige solid). 

M.p. c. 85 ºC  V.p. 0.093 mPa (20 °C) 

KOW logP = 2.13 (pH 7, 22 ºC). 

Henry 5.741 × 10-5 Pa m3 mol-1

S.g./density c. 1.31 (20 °C) 

Solubility In water 430 mg/l (20 ºC). In acetone, chloroform >1000, ethyl acetate 590, ethanol 200 (all in g/kg, 20 ºC).  Stability Stable for at least 2 years at up to 40 ºC.   

Biochemistry Inhibits cell division by blocking protein synthesis. 

Mode of action Selective herbicide, absorbed by the hypocotyls and roots. Inhibits germination. 

Uses Pre-emergence and early post-emergence control of winter and annual grasses (such as Alopecurus myosuroides, Apera spica-venti, Avena fatua, Digitaria sanguinalis, Echinochloa crus-galli, Poa annua and Setaria spp.) and broad-leaved weeds (Amaranthus, Anthemis, Matricaria, Polygonum, Sinapis, Solanum, Stellaria, Urtica and Veronica spp.) in artichokes, broccoli, asparagus, Brussels sprouts, cabbages, cauliflower, sweetcorn, garlic, horseradish, kale, leeks, maize, white mustard, onions, peanuts, pome fruits, potatoes, radish, rape, soya beans, stone fruits, strawberries, sugar cane, sunflowers, tobacco and turnips. Applied at 1.0-1.5 kg a.i./ha. 

Formulation types SC.

Product analysis by rp hplc with u.v. detection (CIPAC Handbook, 1992, E, 134-8). Methods for residue analysis (based on 2,6-dimethylaniline) available from BASF.

MAMMALIAN TOXICOLOGY

Oral Acute oral LD50 for rats 2150 mg/kg. 

Skin and eye Acute percutaneous LD50 for rats >6810 mg/kg. No irritation of mucous membranes (rabbits).  Inhalation LC50 (4 h) for rats >34.5 mg/l. 

NOEL In long-term feeding trials, NOEL for rats 3.6, dogs 8 mg/kg b.w. 

ADI 0.036 mg/kg. 

Toxicity class WHO (a.i.) III (Table 5)