98%TC 50%EC 25%EC spiroxamine Fungicide CAS No.:118134-30-8 CAS NO.118134-30-8

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FAO Standards

Toxicity:

Oral	Acute oral LD50 for male rats c. 595, female rats 500-560 mg/kg.
Skin and eye	Acute percutaneous LD50 for male rats >1600, female rats c. 1068 mg/kg b.w. Severe skin irritant; not an eye irritant (rabbits).
Inhalation	LC50 (4 h) for male rats c. 2772, female rats c. 1982 mg/m3.
NOEL	(2 y) for rats 70, mice 160 mg/kg diet; (1 y) for dogs 75 mg/kg diet.
ADI	0.025 mg/kg b.w.
Other	Not genotoxic; no specific effects on reproduction.
Toxicity class	WHO (a.i.) II; EPA (formulation) II
EC hazard	Xn; R20/21/22\| Xi; R38\| R43\| N; R50, R53

Application:

Common name	Spiroxamine
Formulation	Spiroxamine 98%TC, 25%+16.7%tebuconazole+4.3%triadimenolEC,80%EC
Biochemistry	Sterol biosynthesis inhibitor, acting mainly by inhibition of D14-reductase.
Mode of action	Protective, curative and eradicative systemic fungicide. Readily penetrates into the leaf tissue, followed by acropetal translocation to the leaf tip. Uniformly distributed within the whole leaf.
Uses	Control of powdery mildew in cereals (Erysiphe graminis), at 500-750 g/ha, and in grapes (Uncinula necator), at 400 g/ha. Also gives good control of rusts (Rhynchosporium and Pyrenophora teres), together with certain side-effects against Septoria diseases. Penetration studies have shown that tank mixes of spiroxamine and triazoles can positively influence the uptake of triazoles in plants.